NMS-P626

Overview

NMS-P626 is an inhibitor of TRKA , TRKB , and TRKC , with IC 50 values of 8 nM, 7 nM, and 3 nM, respectively. NMS-P626 inhibits the growth of KM12 cells by suppressing the phosphorylation of TPM3-TRKA and downstream signaling in KM12 cells, with an IC 50 of 19 nM for KM12 cells. NMS-P626 can be used in colorectal cancer research.

Application

Products | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Trk Receptor

Product Information

• Catalog No.: HY-164514
• CAS No.: 942471-37-6
• Molecular Formula: C28H35F2N7O4S
• Molecular Weight: 603.68
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source