ONC213

Overview

ONC213 is an orally active αKGDH inhibitor. ONC213 can suppress mitochondrial respiration and elevate α-ketoglutarate levels by inhibiting αKGDH activity. ONC213 can induce cells apoptosis by inducing mitochondrial stress response and inhibiting translation of MCL-1 . ONC213 can be used for the research of cancer , such as acute myeloid leukemia research (AML).

Application

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Product Information

• Catalog No.: HY-164515
• CAS No.: 1977540-13-8
• Molecular Formula: C23H22F2N4O
• Molecular Weight: 408.44
• Purity: 99.86%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source