PMMB-187

Overview

PMMB-187 is a selective STAT3 inhibitor with an IC 50 value of 1.81 μM for MDA-MB-231 cells. PMMB-187 induces apoptosis ( Apoptosis ) in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity, nuclear translocation, and downstream target gene expression, while also reducing mitochondrial membrane potential, generating reactive oxygen species (ROS), and upregulating the expression levels of apoptosis-related proteins. PMMB-187 has potential applications in cancer research.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > STAT

Product Information

• Catalog No.: HY-164521
• CAS No.: 2162952-37-4
• Molecular Formula: C27H23BrN2O6S2
• Molecular Weight: 615.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source