SIK2/3-IN-2

Overview

SIK2/3-IN-2 (compound 12, compound I-200) is a potent SIK2/3 inhibitor ( SIK2 IC 50 = 65 nM, SIK3 IC 50 = 14 nM). SIK2/3-IN-2 is also a p21-activated protein kinase ( PAK ) 1 inhibitor with a K i of 20.7 nM. SIK2/3-IN-2 can be used for hyperproliferative diseases and cancer research, such as Paclitaxel ( HY-B0015 )-resistant ovarian cancer .

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Myelodysplastic Syndrome | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Salt-inducible Kinase (SIK) | Products > Signaling Pathways > PAK

Product Information

• Catalog No.: HY-164534
• CAS No.: 1648864-21-4
• Molecular Formula: C25H25ClN6O3
• Molecular Weight: 492.96
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source