PKCTheta-IN-2

Overview

PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor with an IC 50 of 0.25 nM. PKCTheta-IN-2 shows good selectivity over a wide range of kinases, including the PKC subfamily (30 kinases). PKCTheta-IN-2 inhibits the IL-2 production in a mouse ( IC 50 of 682 nM).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PKC

Product Information

• Catalog No.: HY-164756
• CAS No.: 1810742-60-9
• Molecular Formula: C24H23N5O2
• Molecular Weight: 413.47
• Purity: 99.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source