PIN1 degrader-1

Overview

PIN1 degrader-1 (Compound 158H9) is the inhibitor for proline cis trans isomerase ( Pin1 ) with an IC 50 of 21.5 nM. PIN1 degrader-1 forms covalent bond with Cys113 of Pin1 , induces conformational changes in Pin1 , reduces its stability, and leads to a proteasome-dependently degradation. PIN1 degrader-1 inhibits the cell viability of multi cancer cells, and can be used in cancer research.

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PIN1

Product Information

• Catalog No.: HY-164895
• CAS No.: 3080918-50-6
• Molecular Formula: C30H32Cl2N6O4
• Molecular Weight: 611.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source