Keap1-Nrf2-IN-23 (compound 56) is an inhibitor of the Keap1–Nrf2 PPI ( IC 50 =16.0 nM). Keap1-Nrf2-IN-23 binds to Keap1 with a K d value of 3.07 nM. Keap1-Nrf2-IN-23 has oral activity.
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