Antiproliferative agent-64

Overview

Antiproliferative agent-64 (Compound 76) is an inhibitor for eukaryotic translation initiation factor 4E ( eIF4E ), that block the secondary structure of mRNA , thereby inhibiting protein translation. Antiproliferative agent-64 inhibits the 5' untranslated region (5'UTR) of c-Myc ( c-myc 5'UTR) with an EC 50 of 1.2 nM, inhibits 5'UTR encoding tubulin (tub 5'UTR) with an EC 50 of 40 nM. Antiproliferative agent-64 inhibits the proliferation of MDA-MB-231 with an EC 50 of 7 nM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Microtubule/Tubulin

Product Information

• Catalog No.: HY-168326
• CAS No.: 1139263-21-0
• Molecular Formula: C29H28N2O6
• Molecular Weight: 500.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source