HDAC1-IN-8

Overview

HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor with IC 50 values of 11.94, 22.95, >500 µM for HDAC1 , HDAC6 , HDAC8 , respectively. HDAC1-IN-8 shows antiproliferative activity. HDAC1-IN-8 induces cell cycle arrest at G1 and G2/M. HDAC1-IN-8 induces autophagy . HDAC1-IN-8 shows anticancer activity and has the potential for the research of lung cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-168477
• CAS No.: 3066143-73-2
• Molecular Formula: C22H24N2O4
• Molecular Weight: 380.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source