WX-02-23

Overview

WX-02-23 is a small-molecule probe that stereoselectively and site-specifically binds to C258 of FOXA1 and C1111 of SF3B1 . WX-02-23 remodels FOXA1's chromatin binding and pioneer activity in a DNA-dependent manner, disrupts spliceosome assembly, and enhances the thermal stability of SF3B1 . WX-02-23 inhibits tumor cell proliferation and induces apoptosis . WX-02-23 can be used for research on cancers such as prostate cancer .

Application

Products | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > SF3B1 | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > FOXA

Product Information

• Catalog No.: HY-168534
• CAS No.: 2929223-35-6
• Molecular Formula: C26H25N3O5
• Molecular Weight: 459.49
• Purity: 99.88%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source