MZ82

Overview

MZ82, Ko 143 ( HY-10010 ) derivative, is a ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor with the IC 50 of ~23 nM. MZ82 not only shows greatly improved metabolic stability over Ko 143 ( HY-10010 ) in liver microsomes but also in mice, and is able to penetrate into the brain.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > BCRP

Product Information

• Catalog No.: HY-168572
• CAS No.: 2944457-11-6
• Molecular Formula: C26H29N3O3
• Molecular Weight: 431.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source