WEE1 degrader 1

Overview

WEE1 degrader 1 (Compound 10) is a CRBN -dependent molecular glue degrader of WEE1 and casein kinase 1α ( CK1α ) with sub-2 nM DC 50 values for both targets. WEE1 degrader 1 can be used for the research of acute lymphoblastic leukemia, acute monocytic leukemia, acute promyelocytic leukemia, colorectal adenocarcinoma, diffuse large b cell lymphoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Wee1

Product Information

• Catalog No.: HY-168654
• CAS No.: 3090685-34-7
• Molecular Formula: C30H31N5O3
• Molecular Weight: 509.60
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.91 mM); Clear solution
• Availability: In-stock

Source

Original product source