Darbufelone mesylate

Overview

Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF 2α and LTB 4 production. Darbufelone potently inhibits PGHS-2 ( IC 50 = 0.19 μM) but is much less potent with PGHS-1 ( IC 50 = 20 μM).

Application

Products | Products > Disease Areas > Arthritis | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Rheumatoid Arthritis | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Prostaglandin Receptor | Products > Signaling Pathways > Leukotriene Receptor

Product Information

• Catalog No.: HY-101438A
• CAS No.: 139340-56-0
• Molecular Formula: C19H28N2O5S2
• Molecular Weight: 428.57
• Purity: 99.65%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: 5.5 mg/mL (12.83 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source