FAK-IN-24

Overview

FAK-IN-24 (Compound 9f) is a FAK inhibitor ( IC 50 : 0.815 nM). FAK-IN-24 induces DNA damage and apoptosis . FAK-IN-24 has anti-glioblastoma activity. FAK-IN-24 inhibits proliferation of glioblastoma cell lines U87-MG (IC 50 = 15 nM) and U251 (IC 50 = 20 nM). FAK-IN-24 inhibits tumor growth in U87-MG xenograft model.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > FAK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-168899
• CAS No.: 3062175-62-3
• Molecular Formula: C39H45Cl2F3N8O3
• Molecular Weight: 801.73
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source