BRD-K20733377

Overview

BRD-K20733377 is an inhibitor for Bcl-2 , and exhibits selective cytotoxicity against senescent cells, that inhibits the viability of Etoposide ( HY-13629 )-induced IMR-90 senescent cell with an IC 50 of 10.7 μM. BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21 and KI67 in aged mouse model.

Application

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Product Information

• Catalog No.: HY-169265
• CAS No.: 452350-43-5
• Molecular Formula: C23H18N4O3S
• Molecular Weight: 430.48
• Purity: 99.50%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.61 mM); Suspended solution
• Availability: In-stock

Source

Original product source