ATM Inhibitor-11

Overview

ATM Inhibitor-11 (Compound 1) is an inhibitor for ATM with an IC 50 of 0.32 nM. ATM Inhibitor-11 inhibits the KAP1 phosphorylation with an IC 50 of 0.97 nM. ATM Inhibitor-11 exhibits high exposure in the brain, heart and plasma of ICR mouse. ATM Inhibitor-11 exhibits anti-tumor efficacy in NCI-H441 xenograft mouse model.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ATM/ATR

Product Information

• Catalog No.: HY-169310
• CAS No.: 2878473-51-7
• Molecular Formula: C27H33FN6O2
• Molecular Weight: 492.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source