NPC26

Overview

NPC26 is a small molecule mitochondrial disruptor with anti-tumor activity. NPC-26 shows significant anti-proliferative and cytotoxic effects on CRC cell lines (HCT-116, DLD-1, and HT-29). NPC26 can damage mitochondrial function, leading to the opening of the mitochondrial permeability transition pore (mPTP) and the production of reactive oxygen species , ultimately inducing cell death. NPC-26 can kill CRC cells by activating the AMP-activated protein kinase ( AMPK ) signaling pathway.

Application

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Product Information

• Catalog No.: HY-169652
• CAS No.: 864860-32-2
• Molecular Formula: C19H23N3O5S2
• Molecular Weight: 437.53
• Purity: 98.0%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source