STAT3-IN-38

Overview

STAT3-IN-38 (Compound 4m) is an inhibitor of STAT3 (K D of rhSTAT3: 45.33 µM). STAT3-IN-38 binds to the SH2 domain of STAT3 protein and suppresses the STAT3’s phosphorylation at site pTyr705 as well as its downstream genes ( Survivin and Mcl-1 ). STAT3-IN-38 could block cell-cycle and induce Apoptosis in colorectal cancer cells.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > STAT | Products > Signaling Pathways > Survivin | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-169797
• CAS No.: 3033049-16-7
• Molecular Formula: C35H45NO3S
• Molecular Weight: 559.80
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source