MLK3-IN-1 (Compound 37) is a selective inhibitor for mixed-lineage protein kinase 3 ( MLK3 ) with an IC 50 <1 nM. MLK3-IN-1 inhibits FAK with an IC 50 of 15.5 μM. MLK3-IN-1 exhibits good metabolic stability in mouse and human liver microsomes.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Mixed Lineage Kinase | Products > Signaling Pathways > FAK
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