GB2095 is an orally active and selective galectin-3 inhibitor. GB2095 shows superior selectivity for both human ( K D = 0.036 μM) and mouse galectin-3 ( K D = 0.35 μM) over other galectins (such as h-Gal-1/4N/4C/8N/8C/9N/9C and m-galectin-1). GB2095 inhibits tumor growth in syngeneic mouse models of breast and melanoma cancers. GB2095 can be used for breast and melanoma cancer research.
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