STAT1/3-IN-1

Overview

STAT1/3-IN-1 is a potent STAT1/3 inhibitor with potent anti-inflammatory effect. STAT1/3-IN-1 inhibits phosphorylation and nuclear translocation of STAT1/3 to modulate microglial inflammation, reduces LPS ( HY-D1056 )-induced pro-inflammatory cytokines ( NO , IL-1β , IL-6 , and TNF-α ) and inflammatory mediators ( iNOS , COX-2 ). STAT1/3-IN-1 exhibits low toxicity in mice. STAT1/3-IN-1 can be used for the research of neuroinflammation.

Application

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Product Information

• Catalog No.: HY-170621
• CAS No.: 2958649-56-2
• Molecular Formula: C28H25ClN6O5
• Molecular Weight: 560.99
• Purity: 99.23%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (8.91 mM); Clear solution
• Availability: In-stock

Source

Original product source