eIF4A3-IN-1

Overview

eIF4A3-IN-1 is a selective eIF4A3 inhibitor ( IC 50 : 0.26 μM; K d : 0.043 μM) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3 . eIF4A3-IN-1 has anti-tumor and analgesic activities.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Eukaryotic Initiation Factor (eIF)

Product Information

• Catalog No.: HY-101513
• CAS No.: 2095486-67-0
• Molecular Formula: C29H23BrClN5O2
• Molecular Weight: 588.88
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (8.49 mM); Clear solution
• Availability: In-stock

Source

Original product source