OPB-3206

Overview

OPB-3206 is a selective matrix metalloproteinase ( MMP ) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A ( MMP-2 ), gelatinase B ( MMP-9 ) and stromelysin with IC 50 values of 7×10 -7 M, 5×10 -6 M, 5×10 -7 M and 2×10 -6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-171776
• CAS No.: 166245-54-1
• Molecular Formula: C18H25N3O5
• Molecular Weight: 363.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source