GSK3β-IN-2

Overview

GSK3β-IN-2 (Compound S01) is the inhibitor for GSK3β with an IC 50 of 0.35 nM. GSK3β-IN-2 activates Wnt/β-catenin signaling pathway, promotes neurogenesis and neurite growth. GSK3β-IN-2 inhibits Aβ-induced tau hyperphosphorylation at Ser396, reduces the formation of neurofibrillary tangles. GSK3β-IN-2 ameliorates Alzheimer's Disease in zebrafish model.

Application

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Product Information

• Catalog No.: HY-172171
• CAS No.: 3068378-38-8
• Molecular Formula: C25H18N4O
• Molecular Weight: 390.44
• Purity: 98.75%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source