Linrodostat

Overview

Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 ( IDO1 ) inhibitor with an IC 50 value of 1.1 nM in IDO1 -HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO)

Product Information

• Catalog No.: HY-101560
• CAS No.: 1923833-60-6
• Molecular Formula: C24H24ClFN2O
• Molecular Weight: 410.91
• Purity: 99.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (6.08 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source