SHP2-IN-37

Overview

SHP2-IN-37 (compound C5) is a potent and selective SHP2 allosteric inhibitor with an IC 50 of 0.023 μM. SHP2-IN-37 exhibits antiproliferative effect on KYSE-520 and MV-411 cells with IC 50 s of 6.97 and 0.67 μM, respectively

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2

Product Information

• Catalog No.: HY-172911
• CAS No.: 3086289-71-3
• Molecular Formula: C19H22Cl2N4O2S
• Molecular Weight: 441.37
• Purity: 96.36%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution
• Availability: In-stock

Source

Original product source