Hapalindole Q

Overview

Hapalindole Q (Compound (+)-1) is an autophagy ( Autophagy ) inhibitor targeting YAP1 . Hapalindole Q binds to the Hippo pathway transcription factor YAP1 with a K d of 9.13 μM and induces its degradation via the chaperone-mediated autophagy (CMA) pathway. This process inhibits Rab7 -mediated fusion of autophagosomes and lysosomes, thereby reducing overall autophagy levels without affecting lysosomal function. Hapalindole Q holds promise for research in cancer (e.g., liver cancer , breast cancer , etc.).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > YAP

Product Information

• Catalog No.: HY-173150
• CAS No.: 106928-29-4
• Molecular Formula: C21H24N2S
• Molecular Weight: 336.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source