FAK-IN-26

Overview

FAK-IN-26 is a BBB-penetrable Focal Adhesion Kinase ( FAK ) inhibitor ( IC 50 : 0.87 nM). FAK-IN-26 significantly suppresses tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 has potent anti-cancer activity in A549 and SKOV-3 tumor mice models with tumor inhibition rates of 59.15 % and 57.9 %.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > FAK

Product Information

• Catalog No.: HY-173515
• CAS No.: 2801785-12-4
• Molecular Formula: C20H19BrFN5O2
• Molecular Weight: 460.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source