Adenosine-3',5'-bisphosphate is an exoribonuclease XRN1 inhibitor with an IC 50 of 36 nM, a K D of 12 nM, and a K D of 14 nM against human XRN2 . Adenosine-3',5'-bisphosphate binds to the bimetallic active site of human XRN1 , and also binds potently to human XRN2 via its conserved bimetallic active site. Adenosine-3',5'-bisphosphate can be used in research related to non-small cell lung cancer .
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