Temozolomide

Overview

Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.

Application

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Product Information

• Catalog No.: HY-17364
• CAS No.: 85622-93-1
• Molecular Formula: C6H6N6O2
• Molecular Weight: 194.15
• Purity: 99.65%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (6.44 mM); Clear solution
• Availability: In-stock

Source

Original product source