XSJ110

Overview

XSJ110 is a potent irreversible topoisomerase I ( Topo I ) inhibitor with an IC 50 value of 0.133 μM. XSJ110 blocks DNA topoisomerization, induces DNA double-strand breaks, and triggers cell cycle arrest at G 0 /G 1 phase, inducing tumor cell apoptosis . XSJ110 is promising for research of ampullary carcinoma (AC).

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-174151
• CAS No.: 203923-65-3
• Molecular Formula: C23H20N2O5
• Molecular Weight: 404.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source