MT-125 free base

Overview

MT-125 free base is a specific and well-tolerated inhibitor of non-muscle myosin IIA (K i,NMIIA = 2.7 μM) and IIB (EC 50 = 1.7 μM). MT-125 free base can pass through the blood-brain barrier. MT-125 free base induces ferroptosis and DNA damage by increasing the levels of reactive oxygen species (ROS) within tumor cells. MT-125 free base can enhance the PDGFR signaling pathway. MT-125 free base can be used for research on glioblastoma.

Application

Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Myosin | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Akt | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-174406A
• CAS No.: 2404652-80-6
• Molecular Formula: C22H19N3O2
• Molecular Weight: 357.41
• Purity: 98.67%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 3.33 mg/mL (9.32 mM); Clear solution
• Availability: In-stock

Source

Original product source