Tesaglitazar is a dual-target PPARα/γ agonist with an EC 50 of 13.4 μM for rat PPARα and 3.6 μM for human PPARα . Tesaglitazar affects lipid and glucose metabolism by activating PPARα and PPARγ receptors, and has the potential to improve blood sugar and relieve pain. Tesaglitazar can be used to induce in vivo tumor models and can be used in the study of type 2 diabetes, dyslipidemia, and neuropathic pain.
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