WMJ-J-09

Overview

WMJ-J-09 is an HDAC inhibitor with IC 50 values of 7.5 nM ( HDAC1 ), 21.3 nM ( HDAC2 ), 18.4 nM ( HDAC3 ), 90.9 nM ( HDAC8 ), 3.9 nM ( HDAC6 ) and 8715.7 nM ( HDAC4 ). WMJ-J-09 blocks the cell cycle and induces apoptosis in cancer cells. WMJ-J-09 induces cancer cell death through the LKB1-AMPK-p38MAPK-p63-survivin signaling cascade.WMJ-J-09 inhibits HDAC enzyme activity, leading to acetylation of key proteins and thereby regulating cancer cell death. WMJ-J-09 can be used in HCT116 cells and FaDu cells research [1][2] .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > Pim | Products > Signaling Pathways > Survivin | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-174803
• CAS No.: 2416914-29-7
• Molecular Formula: C22H27N3O5S
• Molecular Weight: 445.53
• Purity: 98.44%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source