pro-FTY

Overview

pro-FTY, a FTY720 ( HY-12005 ) anticancer prodrug, is a sphingosine-1-phosphate (S1P) ( HY-108496 ) inhibitor. pro-FTY specifically inhibits S1P signaling in cancer cells using a drug delivery system (DDS) that reacts with acrolein. pro-FTY significantly inhibits the survival of breast cancer cells, including multidrug-resistant cells and its organoids resistant to Paclitaxel ( HY-B0015 ) or Doxorubicin ( HY-15142A ). pro-FTY potently suppresses tumor growth in 4T1 cells or organoids xenograft tumors mice model while avoiding lymphocytopenia.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > LPL Receptor | Products > Signaling Pathways > STAT

Product Information

• Catalog No.: HY-175201
• CAS No.: 3064707-13-4
• Molecular Formula: C33H50N4O4
• Molecular Weight: 566.77
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source