CHI3L1-IN-3

Overview

CHI3L1-IN-3 is a CHI3L1 inhibitor. CHI3L1-IN-3 binds to CHI3L1 with K d s of 13.76 μM and 13.5 μM in MST and SPR assays, respectively. CHI3L1-IN-3 demonstrates extended plasma half-lives and microsomal stability, along with reduced intrinsic clearance. CHI3L1-IN-3 induces dose-dependent cytotoxicity, reduces spheroid mass and inhibits migration in a 3D multicellular glioblastoma (GBM) spheroid model. CHI3L1-IN-3 can be used for the study of GBM.

Application

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Product Information

• Catalog No.: HY-175207
• CAS No.: 3109469-27-1
• Molecular Formula: C30H33N3O6S
• Molecular Weight: 563.66
• Purity: 98.95%
• Storage: Store at room temperature, keep dry and cool. In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: ≥ 2.5 mg/mL (4.44 mM); Clear solution
• Availability: In-stock

Source

Original product source