MU876

Overview

MU876 (Compound 32) is a MUS81 inhibitor with an IC 50 of 0.5 μM. MU876 effectively inhibits MUS81-dependent homologous recombination (HR) and break-induced replication (BIR) pathways. MU876 sensitizes cancer cells to DNA-damaging agents, such as Cisplatin ( HY-17394 ), through impairing their ability to repair DNA lesions. MU876 can be used for cancers chemotherapy research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Endonuclease

Product Information

• Catalog No.: HY-175812
• CAS No.: 1208829-24-6
• Molecular Formula: C24H18N6O3
• Molecular Weight: 438.44
• Purity: 97.00%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source