DNMT-IN-5

Overview

DNMT-IN-5 is a stable and efficient DNA methyltransferase ( DNMT ) inhibitor with high stability and high activity with an IC 50 of 0.78 nM. DNMT-IN-5 exhibits sub-micromolar DNMT3A inhibitory activity, upregulates the expression of DNMT-targeted genes, impairs cell proliferation, and triggers a critical cell cycle arrest. DNMT-IN-5 can be used for the study of p53-depleted colorectal cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA Methyltransferase

Product Information

• Catalog No.: HY-176230
• CAS No.: 3126555-64-1
• Molecular Formula: C16H12BrClO3
• Molecular Weight: 367.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source