FKBP12 ligand-2

Overview

FKBP12 ligand-2 (compound d) is a high affinity ligand targeting FKBP12 . FKBP12 ligand-2 can be used to selectively enhance the binding of heterobifunctional molecules to BRD4, enriching the drug intracellularly through the "CellTrap" effect to form a ternary complex of FKBP12-ligand-BRD4. This ternary complex has inhibitory activity against BRD4, thereby inhibiting the expression of BRD4 target genes (such as MYC) and inducing tumor cell death. FKBP12 ligand-2 can be used for selective cancer research based on differences in intracellular presenter protein levels.

Application

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Product Information

• Catalog No.: HY-176501
• CAS No.: 3036243-81-6
• Molecular Formula: C24H25Cl2N3O4S
• Molecular Weight: 522.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source