FKBP12 ligand-3

Overview

FKBP12 ligand-3 (compound dj) is a high-affinity ligand targeting FKBP12 . FKBP12 ligand-3 can be used to selectively enhance the binding of heterobifunctional molecules to BRD4, enriching the drug intracellularly through the "CellTrap" effect to form a ternary complex of FKBP12-ligand-BRD4. This ternary complex has inhibitory activity against BRD4, thereby inhibiting the expression of BRD4 target genes (such as MYC) and inducing tumor cell death. FKBP12 ligand-3 can be used for selective cancer research based on differences in intracellular presenter protein levels.

Application

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Product Information

• Catalog No.: HY-176502
• CAS No.: 3036374-26-9
• Molecular Formula: C25H27Cl2N3O4S
• Molecular Weight: 536.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source