EMC-AANL-DOX is a legumain-activated prodrug conjugate of Doxorubicin (DOX) ( HY-15142A ). EMC-AANL-DOX shows antitumor activity in mouse models of neuroblastoma (NB), breast cancer (4T1), fibrosarcoma (HT1080), and colorectal cancer liver metastases (CT26). EMC-AANL-DOX can be used for cancer research.
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