M-1111

Overview

M-1111 is a Rapa-Link inhibitor. M-1111 is covalently linked by Rapamycin ( HY-10219 ) and an inhibitor of the active site mTOR . M-1111 has strong inhibitory activity on the mTORC1 signaling pathway ( pS6 and p4E-BP1 ). M-1111 has nanomolar-level inhibitory activity against various cancer cells. M-1111 completely inhibits p4E-BP1 without inhibiting pAkt S473. M-1111 can be used for research on liver cancer , kidney cancer , and colorectal cancer .

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > mTOR

Product Information

• Catalog No.: HY-176948
• CAS No.: 1887095-86-4
• Molecular Formula: C89H134N12O23
• Molecular Weight: 1740.08
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source