KT53 is a highly active, selective, and cell penetrable GSTO1 inhibitor. KT53 can effectively inhibit GSTO1 activity in MDA-MB-435 ( IC 50 = 35 nM) cells. KT53 significantly enhances the killing effect of cisplatin ( HY-17394 ) on MDA-MB-435 cancer cells. KT53 can be used for cancer research.
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