EGFR-IN-177

Overview

EGFR-IN-177 is a potent EGFR inhibitor with IC 50 s of 0.32, 1.04, 0.65, 0.67, 0.48, 0.55 and 0.38 nM against EGFR L858R , EGFR L858R/T790M , EGFR L858R/T790M/C797S , EGFR D746-750 , EGFR D746-750/C797S , EGFR D770_N77linsNPG , and EGFR WT . EGFR-IN-177 inhibits lung cancer proliferation and EGFR phosphorylation. EGFR-IN-177 can be used for the study of cancers such as non-small cell lung cancer .

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-178283
• CAS No.: 3062177-59-4
• Molecular Formula: C27H36N8O3
• Molecular Weight: 520.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source