DGKα&ζ-IN-2

Overview

DGKα/ζ-IN-2 is a potent, orally active and selective dual DGKα/ζ inhibitor with IC 50 values of 23 nM (DGKα) and 1.2 nM (DGKζ). DGKα/ζ-IN-2 exhibits selectivity over other DGK isoforms, such as DGKβ and DGKγ. DGKα/ζ-IN-2 shows robust and dose-dependent immune activation in the presence of antigen presentation in an OT-1 murine model. DGKα/ζ-IN-2 can be used for antitumor immunity.

Application

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Product Information

• Catalog No.: HY-178327
• CAS No.: 3039488-61-1
• Molecular Formula: C35H34F4N6O2
• Molecular Weight: 646.68
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source