BRK/PTK6-IN-1

Overview

BRK/PTK6-IN-1 (Compound 51) is a highly efficient and selective BRK inhibitor ( IC 50 = 3.37 nM, K d = 44 nM). BRK/PTK6-IN-1 can reduce MMP-9 protein expression and inhibit IGF-1 induced AKT phosphorylation in MDA-MB-231 cells. BRK/PTK6-IN-1 significantly inhibits migration, invasion, and colony formation but does not affect cell proliferation. BRK/PTK6-IN-1 is often used in the research of breast cancer and other cancers.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > BRK | Products > Signaling Pathways > Akt | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-178460
• CAS No.: 3103652-60-1
• Molecular Formula: C12H10FN5O
• Molecular Weight: 259.24
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source