CT 32228 is an inhibitor of lysophosphatidic acid acyltransferase-β ( LPAAT-β ). CT 32228 inhibits tumor cell growth. CT 32228 exhibits IC 50 values of around 0.1-0.8 μM in various leukemia cell lines. CT 32228 induces caspase activation in DHL-4 and Ramos cells. CT 32228 induces apoptosis when combined with Rituximab ( HY-P9913 ). CT 32228 results in a 50% xenograft growth delay in vivo. CT 32228 can be studied in research on acute leukemia.
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