XZA-1

Overview

XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase ( HADH ) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 ( CBX4 ) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Acetyl-CoA Carboxylase

Product Information

• Catalog No.: HY-178918
• CAS No.: 1282141-20-1
• Molecular Formula: C15H16N2O2
• Molecular Weight: 256.30
• Purity: 99.59%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (19.51 mM); Suspended solution
• Availability: In-stock

Source

Original product source