APL-5125

Overview

APL-5125 (Compound 61f) is a potent, selective and orally active ATP-competitive CK2α inhibitor with an IC 50 of 0.348 nM and a K i of 0.095 nM. APL-5125 binds to CK2α in a bivalent manner, simultaneously interacting with the ATP-binding site and the αD pocket. APL-5125 exhibits antitumor activity and can be used for the research of cancer , such as colon cancer .

Application

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Product Information

• Catalog No.: HY-178980
• CAS No.: 2830619-57-1
• Molecular Formula: C27H24F5N3O5
• Molecular Weight: 565.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source