BJH-86 is a soluble mitochondrial complex 1 inhibitor (oxygen consumption rate inhibition IC 50 = 5 μM). BJH-86 exhibits weak inhibitory activity against phosphodiesterase 10A ( PDE10A ) (IC 50 >10 μM). BJH-86 can reduce cellular oxygen consumption and inhibit cancer cell proliferation. BJH-86 can be used for the research of cancer , such as lung cancer .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Phosphodiesterase (PDE)
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